ClinOleic

An olive oil-based lipid emulsion that is associated with fewer infections than soybean oil.¹⁴

See indications Contact Us

Lipids are an integral part of parenteral nutrition (PN), but some lipid emulsions, such as 100% soybean oil, may modulate patient immune response and increase the risk of complications.^3,5 Through 20 years of experience, ClinOleic maintains the lowest soybean oil content of any soy-containing composite lipid emulsion.^6-8ClinOleic also contains 80% olive oil, which has been associated with fewer infections.¹⁴

See full prescribing information

Doctor and a nurse are talking to a patient in a hospital bed

Critically ill patients may be immunocompromised and vulnerable to complications

Major trauma often results in massive impairment of immunologic activity.⁹ Meanwhile, excessive use of 100% soybean oil-based lipids may have pro-inflammatory effects and potentially may put patients at risk for intestinal failure associated liver disease (IFALD) which can be life-threatening.¹⁰ Still, lipids are an integral part of PN as they are a dense source of calories and provide essential fatty acids.¹¹ ClinOleic provides the required energy and essential fatty acids and minimizes the concern with providing more pro-inflammatory Omega-6 fatty acids associated with lipids based solely on soybean oil.¹²

Olive oil-based PN

Olive oil is rich in long chain Omega-9 monounsaturated fatty acids (MUFAs) with fewer polyunsaturated fatty acids (PUFAs) than the fatty acids contained in soybean and fish oil.¹³ Olive oil-based lipid emulsions may avoid the impairment of the immune response associated with omega-6 PUFAs and may achieve an inflammatory neutral effect.¹²

Graph showing total infections, no. of patients infected, lungs infections & no. of nonspecified infections

A three-chamber bag containing ClinOleic has been associated with fewer infections than a compounded formulation containing 100% soybean oil

In a large, randomized, prospective, open-label multicenter PN study of 458 patients, parenteral nutrition regimen containing olive oil-based lipid emulsion was associated with fewer infections, provided effective nutrition, and was well tolerated.¹⁷

Aligned with international guidelines

ASPEN guidelines recommend to withhold or limit soybean oil-based lipid emulsions during the first week following the initiation of PN.¹⁵ Additionally, ESPEN guidelines recommend that lipids based solely on soybean oil be avoided.¹¹ ClinOleic has the lowest soybean oil content of any soy-containing composite lipid product on the market, enabling the delivery of essential fatty acids while minimizing the unwanted effects of soybean oil.^6-8,12

Lab technician looking through a microscope lens

ClinOleic

ClinOleic is the lipid emulsion in Baxter’s three-chamber bags Olimel and Numeta. Download the Baxter Parenteral Nutrition Compatibility Guide for compounding compatibility and stability information.

Available Soon

Learn more about Clinical Nutrition

Visit the Clinical Nutrition Resource Library to access additional resources

Resource Library

Therapies

ClinOleic

Critically ill patients may be immunocompromised and vulnerable to complications

Olive oil-based PN

A three-chamber bag containing ClinOleic has been associated with fewer infections than a compounded formulation containing 100% soybean oil

Aligned with international guidelines

ClinOleic

Learn more about Clinical Nutrition

Related Products

Are you interested in additional information about ClinOleic?